| Henry Holcombe 1800-1811 |
Timothy Harley 1872-1879 |
| William Bullein Johnson 1811-1815 |
Sylvanus Landrum 1879-1881 |
| Benjamin Screven 1815-1818 |
J. E. L. Holmes 1881-1891 |
| James Sweat 1819-1822 |
S. A. Goodwin 1892-1897 |
| Thomas Meredith 1822-1824 |
John D. Jordan 1897-1906 |
| Henry O. Wyer 1825-1833 |
W. Lowndes Pickard 1907-1914 |
| Josiah S. Law 1834-1835 |
J. Judson Taylor 1915-1918 |
| Charles B. Jones 1836-1837 |
Luther Rice Christie 1918-1921 |
| Joseph G. Binney 1837-1843 |
Norman W. Cox 1922-1927 |
| Henry O. Wyer 1844-1845 |
John E. White 1927-1931 |
| Albert Williams 1845-1847 |
Arthur M. Jackson, D. D. 1931-1941 |
| Joseph T. Robert 1847-1849 |
Leroy G. Cleverdon, Ph.D. 1942-1961 |
| Thomas Rambaut 1849-1855 |
William Forrest Lanier 1962-1969 |
| Joseph B. Stiteler 1856 |
Thomas D. Austin 1970-1988 |
| Samuel G. Daniel 1856-1859 |
Fred W. Andrea III 1989-1993 |
| Sylvanus Landrum 1859-1871 |
John M. Finley 1994-present |